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Chromosome 21 – Netflix Series Review

Chromosome 21 is a new Netflix series from Chile (org. title: Cromosoma 21). In other words, it’s a Spanish language production and the genre is crime-thriller. The series begins when the police are called out to a scene where someone has been murdered.

There they find a young man with Down syndrome. He is the only one there and has blood on him, so they arrest him and bring him in. People with Down syndrome have an extra Chromosome 21, which is where the title comes from.

Continue reading our Chromosome 21 series review below. There are eight 45-minute episodes in the series which is on Netflix (in select countries including the US) from February 8, 2023.

A very different premise for a murder investigation

When the series begins, the young man with Down syndrome, Tomás (Sebastián Solorza), is found at the scene of the crime and has blood on him. He also grabs onto a metal rod, when the police approach him and ask him to put his hands up. Don’t worry, the actual arrest is very peaceful once they realize that he has Down syndrome. Also, he is completely compliant.

However, getting him to talk is more difficult. Not because he can’t but whether it’s PTSD or something else keeping him from explaining what happened, is the first of many questions that need to be answered.

The judge is clearly uncomfortable and wants to hear from the suspect, Tomás (or Tommy, as he goes by). Early on, the lead homicide detective,  Mariana Enríquez (Valentina Muhr) goes to a theater group called “Down UP” where all the actors have Down syndrome.

There the teacher, Sofía (Claudia Di Girólamo) is quick to remind her that people with Down syndrome have unique personalities. Just like anyone else. Read More…

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